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West Nile Virus Fact Sheet for Randolph County MissouriSmallpox Vaccine - Frequently Asked Questions

When was smallpox eradicated?
Why is it a threat now?
Are those who were immunized for smallpox prior to 1971 protected?
Can the public health system really mass vaccinate thousands of people?
How soon after I have been exposed can I still be vaccinated and be protected?
Why not vaccinate the entire population now?
So what is the difference between today and the vaccination programs we used to have?
If I have been exposed to a smallpox case, why should I get the vaccine, which can have serious side effects?
Will I be forced to take the vaccine, even if I have been exposed?
Who will pay for mass vaccination?
How will we recruit volunteers?
How will we train volunteers, such as nurses to administer the shots?
What is one of the most important things state and local public health agencies can do at this time?
Whom should I contact if I want to volunteer?
More Information

When was smallpox eradicated?
Routine smallpox vaccination was stopped in the United States in 1971. Smallpox was eradicated in 1980 and the last known case in the United States was in an immigrant in 1978.

Why is it a threat now?
Smallpox virus has been researched and developed as an experimental biological agent of mass destruction by several countries. Some countries or groups may still have stores of smallpox virus and may deliberately release the virus as an act of war.

Are those who were immunized for smallpox prior to 1971 protected?
Although, some immunity may be present for persons immunized previously, we cannot answer with any certainty how protected a person might be from a vaccine administered over thirty years ago.

Can the public health system really mass vaccinate thousands of people?
Yes, with the help of the private medical sector, volunteers, fire, police and the State Emergency Management Agency (SEMA) we can obtain adequate amounts of vaccine within 12 hours, set up dispensing sites and fully vaccinate thousands of people within the necessary four-day time period.

If one or more cases of smallpox were identified, an immediate surveillance and containment strategy would be instituted. It would include identification of infected persons through intensive surveillance and isolation of infected persons. It would also include ring vaccination, i.e., vaccination of household contacts and other close contacts of infected persons (i.e., primary contacts), and vaccination of household and other potential contacts of the primary contacts (i.e., secondary contacts). In addition, depending on the specific circumstances, vaccination of a larger population of persons might also be undertaken. The recently released "Smallpox Vaccination Clinic Guide" from CDC is a very useful tool in helping us prepare in advance for situations in which vaccination of large numbers of persons is necessary.

How soon after I have been exposed can I still be vaccinated and be protected?
Receiving smallpox vaccine within 4 days of exposure to smallpox will decrease your chances of becoming sick, or of developing serious (perhaps fatal) illness.

Why not vaccinate the entire population now?
Smallpox vaccine is a live-virus vaccine which contains vaccinia (not smallpox) virus, and which does have severe and life-threatening side effects for some people. CDC estimates that 1 person in 10,000 who receives the vaccine will have serious side effects that require a doctor's care. Also, if the vaccine were to be given to everyone in the United States, it is estimated that 350 to 500 people would die from the vaccine. That is about 1 or 2 deaths for each million doses of smallpox vaccine administered.

Certain people should not receive the vaccine (unless they have actually been exposed to the virus). These include: pregnant women; people with certain skin conditions - especially eczema; and people with weakened immune systems, such as those who have received a transplant, are HIV-positive, or are receiving treatment for cancer.

So what is the difference between today and the vaccination programs we used to have?
Recommendations for the use of smallpox vaccine, both in the past as well as today, take into account the risk of smallpox disease versus the risk of complications from the vaccine. When smallpox was seen as a substantial threat to the population, vaccination was recommended. However, by the early 1970's it was judged that the risk of vaccine complications outweighed the threat of endemic smallpox, and routine childhood smallpox vaccination was discontinued in the United States in 1971. Routine vaccination of health care workers ended in 1976, and among military recruits in 1990. In recent years, with no confirmed cases of smallpox occurring, and the risk of a bioterrorist attack assessed as low, vaccination of the general population was not recommended because the potential benefits of vaccination were not seen to outweigh the risks of vaccine complications. Today, with continued reports of possible future use of smallpox virus by bioterrorists (and with the increased availability of smallpox vaccine), the Federal government is in the process of developing guidelines for the pre-event (i.e., before a case(s) of smallpox is diagnosed) use of the vaccine. At this point in time, which groups of people will be recommended to receive the vaccine remains unclear.

Also, the following points need to be kept in mind when considering our present situation:

First, we have many more immunocompromised individuals, such as chemotherapy patients, organ transplant recipients, and HIV-infected persons. These individuals would be at increased risk for serious adverse reactions following smallpox vaccination.

Secondly, as mentioned above, smallpox vaccine is a live-virus vaccine which contains vaccinia (not smallpox) virus. Vaccinia virus is present in the sore that develops at the site of the vaccination, and can be transmitted through direct contact (e.g., contaminated hands) to others. This appears to be a generally rare occurrence, but can potentially result in serious illness in some persons who are contacts of smallpox vaccines (particularly persons who have certain skin conditions or are immunocompromised). Because of these concerns, when smallpox vaccine is given in non-emergency situations, persons whose household contacts have active eczema, or whose household contacts have a history of eczema, should not be vaccinated. Also, persons should not be vaccinated in non-emergency situations if they have household contacts with certain conditions that result in a weakened immune system (e.g., certain malignancies, certain medications, organ transplants, HIV infection), or if they have household contacts who are pregnant or who have certain other skin conditions in addition to eczema.

Finally, if exposed to an actual case of smallpox the risk of contracting smallpox is much greater than the risk of severe side effects from the vaccine. However, in a non-emergency vaccination situation, even one case of severe vaccine side effects will most likely be widely publicized and result in the public's reluctance to be vaccinated should an actual case of smallpox appear.

If I have been exposed to a smallpox case, why should I get the vaccine, which can have serious side effects?
If you have been exposed to an actual case of smallpox, the risk of smallpox infection and the development of serious disease are much greater than the risk of severe side effects from the vaccine.

Will I be forced to take the vaccine, even if I have been exposed?
No, if you are exposed to a case of smallpox, and you decide not to take the vaccine you will be closely monitored for 18 days for the signs and symptoms of smallpox. Those members of your household who cannot, because of medical conditions, or who decide not to be vaccinated will need to move, elsewhere, for that 18 day period of time. You will be allowed to leave your home, but not travel more than one hour away, in case you begin to show signs and symptoms.

Who will pay for mass vaccination?
The Federal Government will provide the vaccine. Distribution and dispensing costs associated with a mass vaccination program will be borne by the state and local governments.

How will we recruit volunteers?
The State and Local governments are developing plans for working with agencies such as the Red Cross who are experts in volunteer management and with professional associations such as pharmacists, physicians and nurses to develop lists of potential volunteers.

How will we train volunteers, such as nurses to administer the shots?
State and local plans will include working with current volunteer organizations such as the Red Cross as well as experts in CDC to provide necessary training. Local jurisdictions will be conducting drills to provide volunteer training opportunities as well.

What is one of the most important things state and local public health agencies can do at this time?
We need to educate and inform the public so that they can participate in their own defense in the event of a biological, chemical or nuclear attack. Understanding who public health is and how public health works to protect citizens is an essential component of an individual's or family's ability to prepare for the event and to follow the recommendations of the Centers for Disease Control and Prevention, Missouri Department of Health and Senior Services and the local public health agency.

Whom should I contact if I want to volunteer?
Contact a local emergency response volunteer organization in your area such as the Red Cross or your local fire department, or contact your professional association or licensing board.

More Information . . .

DHSS web site: www.dhss.state.mo.us; DHSS toll free number for emergencies and disease reporting 800-392-0272, available 24 hours a day, 7 days a week; your local public health agency.



If you have any questions or need additional information please contact us. We'll be glad to help.


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